Dr. Edward Yu

People
Professor

Dr. Edward Yu, Professor, received his Ph.D. from the University of Michigan at Ann Arbor in 1997. After working as an NIH postdoctoral fellow at University of California-Berkeley, Dr. Yu joined the faculty at Iowa State University in 2004. He is currently a professor of Chemistry and of Physics & Astronomy. Dr. Yu's research focuses on elucidating the structure and function of membrane proteins using x-ray crystallography. 

We currently focus on studying bacterial antibiotic resistance mediated by active multi-drug efflux transporters. Our long-term goal is to elucidate the structures and fundamental mechanisms that give rise to multiple drug recognition and extrusion in these multi-drug transporters. In addition, our laboratory addresses fundamental questions regarding the nature of multi-drug recognition and gene regulation in transcriptional regulators. These regulators control the expression of multi-drug efflux transporters in bacteria by sensing the presence of a variety of structurally unrelated toxic compounds in the environment. Our experimental approach mainly utilizes x-ray crystallography to elucidate toxic chemical binding and export by these membrane efflux transporters.

Area of Expertise: 
Bioinformatics
Education: 
Ph.D.,University of Michigan, 1997