Quantitative and statistical genetics, including the integration of quantitative and molecular genetics and genomics for QTL mapping, genome-wide association studies, and genomic prediction and selection; design and economic aspects of breeding programs for livestock.
- Methods for economic evaluation of breeding programs in competitive markets
- Methods for simulation of breeding programs that combine stochastic and deterministic models
- Design and evaluation of dairy breeding programs to capitalise on reproductive technologies
- Analytical methods to derive asymptotic responses to selection on BLUP breeding values that account for the effects of selection on genetic variance
- Effects associated with genetic markers under the infinitesimal genetic model
- Genetic analysis and national genetic evaluation systems for somatic cell score, longevity, and dystocia for dairy cattle.
- Derivation of economic values and development of total economic index for dairy bulls in Canada
- Use of random regression models for analysis of test-day data
- Optimal selection on non-linear profit functions over multiple generations through the use of optimal control theory
- Marker-assisted selection and optimal selection to resolve the conflict between short- versus long-term responses with marker-assisted selection
- Statistical methods for QTL mapping and their application to detect genes and QTL in pigs.
- Evaluation of measures of linkage disequilibrium
- Comparison of methods for linkage disequilibrium analysis
- Use of high-density SNP genotyping for genomic selection, including improvement of crossbred performance
- Implementation of genomic selection using low-density SNP panels
- Experimental evaluation of genomic selection in layer chickens
- Selection index methods for evaluation of marker-assisted and genomic selection
- Genetic and biological aspects of residual feed intake in pigs; development of RFI research consortium.
- Genome-wide association study for host response to PRRS in pigs; Discovery of major QTL on chromosome 4.
- Identification of Severe Combined Immuno-Deficiency (SCID) in pigs and development of SCID pigs for biomedical research.